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Erythema Multiforme

Medically reviewed by: Yamini Durani, MD

What Is Erythema Multiforme?

Erythema multiforme is an allergic reaction. It causes a rash of spots with dark centers and pale red rings that look like a target or "bulls-eye." Some spots can have a small blister or scab in the middle.

What Are the Signs & Symptoms of Erythema Multiforme?

Erythema multiforme (air-uh-THEE-muh mul-teh-FOR-mee) starts with pink or red blotches. They grow over a few days into round spots that look like targets with red, pink, and pale rings.